Sublingual Immunotherapy (SLIT) in the UK – A Needle-Free Path to Allergy Relief
Tired of Ongoing Hay Fever or Allergies due to Dust Mite, Mould or Pet Allergens?
If seasonal or environmental allergies affect your day-to-day life, sublingual immunotherapy (SLIT) offers an effective treatment option—without the need for injections. Available privately and in some NHS Clinics in the UK, SLIT is a proven and MHRA approved (for some products) therapy for patients struggling with persistent allergic rhinitis, asthma or conjunctivitis triggered by allergens such as pollen, dust mites or pet dander.
Studies also suggest that early intervention with SLIT in children with allergic rhinitis may be effective in preventing the onset of asthma.
SLIT is safe, easy to use and administered at home. It delivers tiny doses of allergens under the tongue to gradually retrain the immune system, helping reduce the frequency and severity of allergic reactions over time.
Available for Adults & Children | Needle-Free | Paediatric & Adult Consultations | Personalised Treatment Plans
✔ Safe & evidence-based food allergy treatment
✔ Led by world-renowned allergy specialists
✔ Personalised care for children & adults
✔ Safe & evidence-based food allergy treatment ✔ Led by world-renowned allergy specialists ✔ Personalised care for children & adults
★★★★★
“Parenting a child with allergies is scary, frustrating and bewildering with conflicting information and opinion. Seeing Prof. Du Toit and the team was life changing. To be seen, heard and understood; to know that you were getting the most up to date evidence based information and advice was a revelation. He is also very kind, gentle and child-centred. Would highly recommend to all parents with an allergy child.”
What Is Sublingual Immunotherapy UK?
Sublingual immunotherapy (SLIT) is a clinically proven allergy treatment available in the UK.
SLIT involves placing a small tablet or drops containing allergen extracts under the tongue daily to retrain the immune system. Over time, this reduces sensitivity to allergens such as pollen (grass, tree or weed), dust mites, mould or pet dander.
SLIT offers a disease-modifying approach to managing allergies—not just symptom relief. SLIT is recommended for individuals with allergic rhinitis, eczema, asthma, or conjunctivitis caused by confirmed environmental allergens.
SLIT generally has a favorable safety profile compared to subcutaneous immunotherapy (allergy shots), with most adverse reactions being mild and localized to the mouth. This makes it a potentially attractive option for longer-term preventative treatment, especially in children.
Who Is Sublingual Immunotherapy UK Ideal For?
SLIT is suitable for both adults and children who:
Suffer from moderate to severe hay fever, or allergic asthma and eczema.
Have confirmed IgE sensitivity to grass, tree and weed pollens or dust mite, mould or pet (cat, dog, horse) allergens
Prefer a non-injection alternative to allergy shots
Are seeking long-term relief from allergy symptoms in the UK
If your allergies are not well controlled by antihistamines, nasal sprays and eye drops, or you're experiencing quality-of-life disruption from seasonal or year-round symptoms, sublingual immunotherapy may be a therapy you wish to consider.
Sublingual Immunotherapy (SLIT) in UK
Acarizax (ALK-Abello): MHRA licensed for house dust mite-induced allergic rhinitis in adults (18-65 years) and adolescents (12-17 years) with persistent moderate to severe symptoms despite symptom-relieving medication. It is also indicated for house dust mite allergic asthma not well controlled by inhaled corticosteroids and associated with mild to severe house dust mite allergic rhinitis in adults.
Grazax (ALK-Abello): MHRA licensed to treat rhinitis and conjunctivitis caused by grass pollen in adults and children (5 years or older).
Itulazax (ALK-Abello): MHRA licensed for Silver Birch tree pollen allergic rhinitis (18 years of age) and used off-label in younger children.
Oraltek (Allergy Therapeutics) is used off-license in some NHS clinics on a named-patient basis for tree pollen, grass pollen, and house dust mite allergies.
Using a shared decision-making process, we initiate the best treatment for you.
Step 1: Initial Consultation & Assessment
A detailed consultation with a UK-based allergy specialist
Step 2: Allergy Testing
To confirm the specific aero-allergen triggering your symptoms
Step 3: SLIT Initiation
The first dose is taken under medical supervision - either in face or on video - to ensure technique and tolerance
Step 4: Daily Treatment at Home
You continue with daily doses over 3 years, annual review, possibility of a booster dose for a year in 5 years.
Step 5: Ongoing Review
We assess your clinical response and make adjustments if needed
Benefits of Sublingual Immunotherapy in the UK
Needle-Free: No injections or weekly clinic visits
Convenient: Take the tablet or drops at home each day
Clinically Proven: Reduces allergy symptoms long term
Safe for Children: Approved for use in patients aged 5+
Reduces Medication Need: Less reliance on antihistamines over time
May decrease the likelihood of allergic wheezing if commenced early
SLIT has been successfully used across Europe for over 20 years and is recommended by allergy specialists in the UK for both children and adults.
Why Choose Us for Sublingual Immunotherapy in the UK
Choosing where to begin your SLIT journey is just as important as the treatment itself. At our clinic, you’re cared for by consultants with deep experience in immunotherapy and allergy management. We take a personalised approach to each case—no generic protocols, just treatments tailored to your diagnosis, goals and lifestyle.
We offer:
Consultant-led care at every step—from diagnosis to long-term review
Access to the latest SLIT formulations for grass, tree, dust and pet allergens
Ongoing support with treatment monitoring and adjustments when needed
Child-friendly options designed for safety and ease of use at home
Minimal wait times, with same-week consultations and responsive follow-up
Our clinic is trusted by GPs, schools and families across the UK. We combine medical expertise with practical, patient-first care, helping you achieve long-term allergy control with confidence.
Frequently Asked Questions
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Yes. SLIT is available both privately and in some NHS clinics. Private allergy services typically offer faster access, broader allergen selection, and consultant-led care.
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Most people begin to notice reduced symptoms after 6–12 months. A full course typically lasts 3–5 years to achieve lasting tolerance.
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SLIT is considered very safe when taken as prescribed. Most side effects (like mild mouth itching) are temporary and self-resolving. Severe reactions are rare.
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Unlike allergy shots (SCIT), SLIT does not require injections or frequent visits to a clinic. It’s taken daily under the tongue at home.
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Yes. SLIT is approved for children aged 5 and older. It’s a convenient and safe option for paediatric patients who have confirmed allergies.
Book Your Sublingual Immunotherapy UK Consultation
If you're looking for trusted private treatment for hay fever, dust mite or pet allergies, speak to our team about sublingual immunotherapy in the UK. We offer tailored allergy care for children and adults, with quick access to testing and long-term support.